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KMID : 0384119870070010047
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Korean Journal of Clinical Pathology
1987 Volume.7 No. 1 p.47 ~ p.48
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Classification of Hematological Diseases by Bone Marrow Examination
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金福伊/Kim, Bog Yi
李惠洙/崔三任/Lee, Hae Soo/Choi, Sam Im
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Abstract
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Bone marrow examination has been the basis of morphological investigation and diagnosis of hematological diseases. Three hundred eighteen cases with significant findings of bone marrow examination observed at the Dept. of Clinical Pathology, Chonbuk National University Hospital, were analyzed and the results observed were as follows;
1. Out of 318 cases, hematological diseases, nonhematological primary diseases with anemia or bleeding tendency, and cases with nonspecific findings were 212 cases (66.7 %), 64 cases (20. 1%1, and 42 cases (13.2%), respectively.
2. The frequency of prevalent group of diseases were as follows; anemia 154 cases (48.4%), leukemia 87 cases(27.4%), and other hematological diseases 58 cases(18. 6
%).
3. Out of 212 hematological diseases, leukemia was 41.0%, iron deficiency anemia 21. 7%, aplastic anemia 9. 9%, hemolytic anemia 8. 5%, idiopathic thrombocytopenic purpura 7. 1% and other diseases 11. 8%.
4. Male to female ratio was 2 : 1 in orve-all leukemia cases and child to adult ratio was 1. 5 : 1. Incidences according to FAB classification and chronicity; acute leukemia 79.3°o and chronic leukemia 20.7%. ALL 39°0 (L 1 17.2%, L 2 21.8%), AML 40.3% (Ml 3.5%, M2 16. 1%, M 3 6.8%, M 4 5.8%, M 5 8. 1%), CML 19. 5%, and CLL 1.2%.
5. Incidences of anemic diseases; iron deficiency anemia 29. 9%, acute and chronic posthemorrhagic anemia 16.3%, hemolytic anemia 15.6%, anemia due to inflamma￢tion 12.9%, and other diseases 25. 3%.
6. Iron deficient dyserythropoiesis in bone marrow was recognized when the level of average serum hemoglobin was 6.6 g/dL. Sex and age incidence of iron deficiency anemia were M : F=0.77: 1 and high incidence in teenagers (58. 7%) and third deca￢des(27%) in female.
7. Aplastic anemia was most common in teenagers, and showed slight male predo-
minance (M : F=1. 2 : 1).
8. idiopathic thrombocytopenic purpura was more common in male (M : F=2. 5 : 1), and 79% of all idiopathic thrombocytopenic purpura patients were in the first decade of age and the remaining were in the fifth decade of age.
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